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This highest-grossing epic science fiction Pocahontas story features blue humanoids and extraordinary visual effects. In talking to one of my friends, a pharmacy resident, we realized the blue skin made us think of an unfortunate side effect of the antiarrhythmic drug amiodarone which can cause bluish-slate gray discoloration of the skin in 1-3% of patients on chronic therapy. Alas, the things medical knowledge does to us.

Image shown under Fair Use, taken from Wikipedia.